inside the early 2010s, the United states was struck by the “opioid disaster”, as illicit fentanyl and new artificial opioids (NSOs) flooded the unlawful drug market. Benzimidazole opioids are µ-opioid receptor (MOR) agonists with antinociceptive Attributes. Even though the potency of Many of these compounds is similar to that of morphine, the